• Gianluca Vanni, Marco Materazzo, Marco Pellicciaro, Sara Ingallinella, Maurizio Rho, Francesca Santori, Maria Cotesta, Jonathan Caspi, Anna Makarova, Chiara Adriana Pistolese, and Oreste Claudio Buonomo.
• Breast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
• In Vivo. 2020 Jun 1; 34 (3 Suppl): 1651-1659.

Background/AimCoronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19.Patients And MethodsBetween the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason.ResultsBC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients.ConclusionCOVID-19-related anxiety could affect patients' decision-making process.Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

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