• Pilar Solves, Nelly Carpio, Federico Moscardo, Teresa Bas, Carolina Cañigral, Claudia Salazar, Blanca Boluda, and Miguel Angel Sanz.
• Blood Bank, Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia 46026, Spain. Electronic address: solves_pil@gva.es.
• Transfus Apher Sci. 2013 Oct 1; 49 (2): 345-8.

Background And ObjectivesSpinal surgery has been shown to have a high blood transfusion requirement. Preoperative autologous blood donation (PABD) is a strategy to reduce the allogeneic transfusions in this subset of patients.Material And MethodsWe retrospectively reviewed transfusion outcome of patients undergoing elective major spinal surgery from 2005 to 2011, and included in the PABD program. Transfusion outcome was compared with a group of patients that did not enter in the program during the same period.ResultsA total of 148 patients were included in the program during the analyzed period. Patients in the PABD program benefited from reduced exposure to allogeneic blood (Odds Ratio: 0.077, 95% confidence interval 0.043-0.140). However, 12.16% (n=18) of these patients received also allogeneic blood (total 40 red blood cell units). Univariate analysis showed the following parameters as significantly predictors of transfusion: inclusion in the program (p<0.000), number of levels fused (Odds Ratio: 1.143, p=0.010), and number of autologous red blood cells donated (Odds Ratio: 1.906, p<0.000).ConclusionsThe preoperative autologous blood donation program designed in our hospital was effective for reducing allogeneic transfusion in mostly young patients under major elective spinal surgery. However and as expected, their inclusion in the program increased the risk to be transfused.Copyright © 2013 Elsevier Ltd. All rights reserved.

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