• Dinesh K Deelchand, James M Joers, Edward J Auerbach, and Pierre-Gilles Henry.
• Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
• Magn Reson Med. 2019 Dec 1; 82 (6): 1984-1992.

PurposeTo demonstrate feasibility and performance of prospective motion and B0 shim correction for MRS in human brain at 7T.MethodsProspective motion correction using an optical camera and linear B0 shim correction using FASTMAP-like navigators were implemented into a semi-LASER sequence. The effect of motion on spectral quality was assessed without and with prospective correction in prefrontal cortex in 11 subjects.ResultsWithout prospective motion and shim correction, motion resulted in considerable degradation of MR spectra (broader linewidth, lower signal-to-noise ratio, degraded water suppression). With prospective motion and shim correction, spectral quality remained excellent despite motion. Prospective motion correction alone was not sufficient to prevent degradation of spectral quality.ConclusionProspective motion and B0 shim correction is feasible at 7T and should help improve the robustness of MRS, particularly in motion-prone populations.© 2019 International Society for Magnetic Resonance in Medicine.

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