• Internal medicine · Jan 2021

    Secondary Minimal Change Disease Due to Pancreatic Cancer Improved by Chemotherapy.

    • Sakue Masuda, Kazuya Koizumi, Hidekazu Moriya, Takashi Nishino, Haruki Uojima, Tomohiko Tazawa, Karen Kimura, Junichi Tasaki, Chikamasa Ichita, Akiko Sasaki, Makoto Kako, Sumi Hidaka, and Madoka Kudo.
    • Department of Gastroenterology Medicine Center, Shonan Kamakura General Hospital, Japan.
    • Intern. Med. 2021 Jan 15; 60 (2): 251-257.

    AbstractWe herein describe an 82-year-old patient who presented with proteinuria and systemic edema. He was diagnosed with minimal change disease (MCD) and was found to have stage III pancreatic cancer. He could not undergo surgical resection due to invasion to the celiac artery and he was thus treated with chemotherapy. After a month of chemotherapy, his proteinuria improved to a normal level. After two months of chemotherapy, computed tomography indicated a partial response to the therapy. MCD can occur as paraneoplastic syndrome in patients with malignant disease, and chemotherapy can be effective for MCD associated with paraneoplastic syndrome.

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