• Sharon Orbach-Zinger, Leonid A Eidelman, Michal Y Livne, Olya Matkovski, Eitan Mangoubi, Adi Borovich, Susan A Wazwaz, Alexander Ioscovich, Zoya Haitov Ben Zekry, Karin Ariche, and Carolyn F Weiniger.
• From the Department of Anesthesia, Rabin Medical Centre and Sackler Faculty of Medicine, Tel Aviv University (SOZ, LAE, MYL, EM, SW), the Department of Anesthesia, Assaf Harofeh Medical Centre, Shamir Medical Centre (OM, ZHBZ), the Department of Obstetrics Gynaecology, Rabin Medical Centre and Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv (AB), the Department of Anesthesia, Shaare Zedek Medical Centre (AI), Hebrew University (AI), the Pain Clinic, Hadassah Hospital, Hebrew University, Jerusalem (KA) and the Department of Anesthesia, Critical Care and Pain Medicine, Tel Aviv Medical Centre, Tel-Aviv, Israel (CFW).
• Eur J Anaesthesiol. 2021 Feb 1; 38 (2): 130137130-137.

BackgroundPostdural puncture headache after accidental dural puncture during labour may lead to chronic sequalae.ObjectivesWe aimed to measure the incidence of postpartum depression, posttraumatic stress disorder, chronic headache, backache and breastfeeding rates after a postdural puncture headache.DesignA retrospective, case-matched cohort study.SettingA review of documented cases of dural puncture and matched case controls occurring at Rabin Medical Center and Shamir Medical Center from 01 January 2012 to 30 September 2018.PatientsThe study cohort consisted of women with a documented postdural puncture headache and the controls were women with uneventful labour epidurals in the same 24-h period. Women were interviewed by telephone.Primary Outcomes MeasureThe primary outcome measure was the incidence of postpartum depression after a postdural puncture headache.ResultsWomen with postdural puncture headache (n = 132) and controls (n = 276) had similar demographic data. The incidence of postpartum depression was 67/128 (52.3%) versus 31/276 (11.2%) for controls, P < 0.0001, 95% confidence intervals of the difference 31.5 to 50.2. Posttraumatic stress disorder was more frequent among women with postdural puncture headache, 17/132 (12.8%) versus controls 1/276 (0.4%), P < 0.0001, 95% confidence intervals of the difference 7.6 to 19.5. Women with postdural puncture headache breastfed less, 74/126 (54.5%) versus controls 212/276 (76.8%), P < 0.0001, 95% confidence intervals of the difference 33.1 to 55.2. Current headache and backache were significantly more frequent among women with postdural puncture headache [current headache 42/129 (32.6%) versus controls 42/276 (15.2%) P < 0.00001, 95% confidence intervals 0.085 to 0.266; current backache 58/129 (43.9%) versus controls 58/275 (21%) P < 0.0001, 95% confidence intervals 14.1 to 33.5].ConclusionWe report an increased incidence of postpartum depression, posttraumatic stress disorder, chronic headache and backache and decreased breastfeeding following a postdural puncture headache. Our findings emphasise the need for postpartum follow-up for women with postdural puncture headache.Trial Registry NumberClinical trial registry number: NCT03550586.Copyright © 2020 European Society of Anaesthesiology and Intensive Care. Unauthorized reproduction of this article is prohibited.

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