• Aust Prescr · Feb 2016

    Review

    Prescribing for patients on dialysis.

    • Brendan Smyth, Ceridwen Jones, and John Saunders.
    • Royal Prince Alfred Hospital, Sydney.
    • Aust Prescr. 2016 Feb 1; 39 (1): 21-4.

    AbstractThe pharmacokinetics of a drug may be altered in patients with renal impairment who require dialysis. Some drugs are contraindicated. The drug's clearance and therapeutic index determine if a dose adjustment is needed. A lower dose or less frequent dosing may be required. Consult a reference source or the patient's nephrologist before prescribing. Start at a low dose and increase gradually. If possible give once-daily drugs after dialysis.

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