• Pak J Med Sci · Nov 2019

    Nuclear magnetic resonance evaluation of inflammatory activity from chronic viral Hepatitis B.

    • Jinghui Dong, Yuan Liu, Huiyi Ye, Weimin An, and Hongwei Ren.
    • Jinghui Dong, Department of Radiology, Medical School of Chinese PLA, Beijing 100853, P. R. China. Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, P. R. China.
    • Pak J Med Sci. 2019 Nov 1; 35 (6): 1565-1569.

    ObjectivesTo discuss the value of applying magnetic resonance diffusion-weighted imaging (DWI) to evaluate inflammatory activity from chronic viral hepatitis B.MethodsOne hundred forty-two patients with chronic viral hepatitis B who received treatment at The Fifth Medical Center of Chinese PLA General Hospital from January 2014 to December 2015 and 20 healthy persons in the control group who were scheduled to undergo nuclear magnetic resonance scanning and DWI examinations (b value = 0, 800 s/mm2), and the apparent diffusion coefficients (ADCs) were measured and compared with the biopsy results of hepatic tissue.ResultsThe ADC value of the group with hepatitis B was lower than that of the healthy group (P<0.05), and the ADC value of the group with mild inflammation (G1) significantly differed from that of the group with moderate inflammation (G2) and that of the group with severe inflammation (G3-G4) (P<0.05).ConclusionsMagnetic resonance diffusion-weighted imaging technology has high clinical value for evaluating the inflammatory activity from chronic hepatitis B, and the measured ADC value corresponds to the pathological grade well, so this method is worth clinical promotion and application.Copyright: © Pakistan Journal of Medical Sciences.

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