• Huseyin Aydogmus, Serhat Sen, and Serpil Aydogmus.
• Huseyin Aydogmus, M.D. Izmir Katip Celebi University Atatürk Research and Training Hospital, Department of Gynecology and Obstetrics, Karabaglar, Izmir, Turkey.
• Pak J Med Sci. 2019 Nov 1; 35 (6): 1627-1630.

ObjectiveTo analyze the clinical outcomes and treatment strategies of patients who underwent conisation in a tertiary hospital clinic.MethodsThe study was designed as a retrospective cohort study. Retrospective data's of 176 patients who underwent conisation due to detection of dysplasia via colposcopic biopsy or cytology-histology discrepancy between 2012 and 2017 were collected. Colposcopy guided biopsies were performed according to HPV positivity and/or abnormal smear results in Izmir Katip Celebi University Ataturk Research and Training Hospital.ResultsIndications for colposcopic biopsies were HPV positivity in 51 patients (29.1%), abnormal smear results in 125 patients (70.9 %). Distribution of abnormal smear results were ASCUS, ASC-H, LSIL, HSIL in 6 (4.8 %), 21 (16.8 %), 24 (19.2%), 74 (59.2%) patients respectively. According to biopsy results, 8 patients (4.4 %) showed no dysplasia where two (1.1%) and 162 (91.5 %) patients were with LSIL and HSIL respectively. Only two were diagnosed with in situ carcinoma. Among 162 patients with HSIL in colposcopic biopsy, 45 showed no dysplasia where four were diagnosed with invasive carcinoma.ConclusionsTo detect high grade cervical lesions colposcopy guided biopsy is gold standard. Although cone biopsy should be performed related to severity of dysplasia in order to sustain the diagnosis and treatment. Contradictory results between colposcopic and cone biopsies should be considered during decision-making process.Copyright: © Pakistan Journal of Medical Sciences.

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