• Pak J Med Sci · Nov 2019

    Biochemical profile changes in stored donor blood for transfusion.

    • May AlMoshary, Eman Al Mussaed, and Maria Arab-Din.
    • Dr. May AlMoshary. MD. Basic Science department (Hematology), College of medicine, Princess Nourah Bint Abdul Rahman University, Riyadh, Saudi Arabia.
    • Pak J Med Sci. 2019 Nov 1; 35 (6): 169717001697-1700.

    ObjectivesThis study's aim was to find out that how various biochemical parameters of donor blood are affected during storage.MethodsThis cross-sectional study was conducted in hematology Unit of Rehman Medical Institute, Peshawar and Fatimid Foundation, Peshawar Khyber Pakhtunkhwa, over a period of six months from June 2018 to November 2018. This study includes 300 healthy volunteer donors. Analysis of stored blood was done at 0, 3, 7, 14- and 21-days interval. Data were recorded and analyzed in SPSS v 20. A p value of less than 0.05 was taken as significant.ResultsThree hundred healthy volunteer donors were included in the study in which 63% were male and 37% were females. Mean age was 26.54±7.3 years with age range from 23-46 years. Out of 300 donors 15.33% were O+, 35.33%, 9.66% B+, 8.33% A+, 7.66% AB+, 7.66% O-, 7% A- and 9% B-. Significant. Changes were observed in serum potassium, LDH, pH, serum chloride, serum sodium and AST levels. (p:<0.001). however, storage did not affect rest of the parameters.ConclusionThis study reveals that during storage certain changes occur in haematological and biochemical parameters which ultimately may put patients at risk.Copyright: © Pakistan Journal of Medical Sciences.

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