• Urooj Bhatti, Zulfiqar Ali Laghari, and Binafsha Manzoor Syed.
• Dr. Urooj Bhatti, Lecturer, Department of Physiology, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Sindh, Pakistan.
• Pak J Med Sci. 2019 Nov 1; 35 (6): 172417291724-1729.

ObjectiveTo assess association of Body mass index (BMI) on respiratory parameters by performing spirometry in apparently healthy adults living in the district Jamshoro and Hyderabad, Sindh, Pakistan.MethodsA cross sectional study was conducted at Department of Physiology, Liaquat University of Medical and Health Sciences Jamshoro, Pakistan from January to September 2015. A total of 180 underweight, normal, overweight and obese participants, aged between 18 to 40 years were included in the study. BMI was calculated by measuring weight and height by BMI scale (RGZ-160) in standing position. Pulmonary parameters were determined by spirometry on Power lab (AD instruments). Pulmonary parameters were compared between subjects in different categories of BMI.ResultsMean age of participants was 21.83±5.88 years and the mean BMI was 25.10±6.55 kg/m2. The study results revealed that except for FVC, which was not statistically significant (p=0.45) all other respiratory parameters were significantly different (p≤0.05) in all BMI categories. Mean FEV1/FVC ratio (93.1 vs. 90.3, 86.4 and 86.6 respectively) was highest among underweight as compared to overweight, obese and normal weight individuals. The mean VT was 1.22 vs. 0.90, 1.01 and 0.84 respectively, IRV was 1.04 vs. 1.18, 1.23 and 1.20 respectively, IC was 2.26 vs. 2.08, 2.25 and 2.05 respectively, VC was 2.63 vs. 2.42, 2.54 and 2.54 respectively, TLC was 2.98 vs. 3.03 vs. 3.18 and 3.17 respectively among underweight, overweight, obese and normal weight participants.ConclusionWe found a significant association between body mass index and pulmonary function parameters. Obesity causes detrimental effects on respiratory system.Copyright: © Pakistan Journal of Medical Sciences.

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