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- Fenna T Phibbs and Peter Hedera.
- Continuum (Minneap Minn). 2010 Feb 1; 16 (1 Movement Disorders): 77-95.
AbstractThe significant contribution of genetic research has resulted in substantial progress in our understanding of the pathophysiology of movement disorders. This will allow for earlier diagnosis of patients with the potential to influence future therapeutics. However, given the complicated patterns of inheritance and consequences for successive generations, a review of the current state of knowledge as well as basic genetic principles is important. In this review we will discuss current classification systems, and clinical and neuropathologic features of the major genetic etiologies for Parkinson disease, dystonia, chorea, and ataxia.
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