• J Res Med Sci · Jan 2016

    A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia.

    • Shu-Chang An, Dong-Hong Yang, Chao-Feng Luo, Xin Chen, Guo-Tian Liu, Yan Weng, Jing-Zhe Liu, Ying Shang, Rui-Qin Wang, and Zhan-Cheng Gao.
    • Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China.
    • J Res Med Sci. 2016 Jan 1; 21: 81.

    BackgroundThis study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients.Materials And MethodsThe cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed.ResultsCompared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033).ConclusionUnique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP.

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