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Best Pract Res Clin Anaesthesiol · Sep 2020
ReviewPharmacogenomics, concepts for the future of perioperative medicine and pain management: A review.
- Alan D Kaye, Cody M Koress, Matthew B Novitch, Jai Won Jung, Ivan Urits, Omar Viswanath, Jordan S Renschler, Edward S Alpaugh, and Elyse M Cornett.
- Louisiana State University Health Shreveport, Department of Anesthesiology, Shreveport, LA, USA. Electronic address: akaye@lsuhsc.edu.
- Best Pract Res Clin Anaesthesiol. 2020 Sep 1; 34 (3): 651-662.
AbstractPharmacogenomics is the study of how genetic differences between individuals affect pharmacokinetics and pharmacodynamics. These differences are apparent to clinicians when taking into account the wide range of responses to medications given in clinical practice. A review of literature involving pharmacogenomics and pain management was performed. The implementation of preoperative pharmacogenomics will allow us to better care for our patients by delivering personalized, safer medicine. This review describes the current state of pharmacogenomics as it relates to many aspects of clinical practice and how clinicians can use these tools to improve patient outcomes.Published by Elsevier Ltd.
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