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- R A Dineen and R K Lenthall.
- Department of Radiology, University Hospital, Queen's Medical Centre, Nottingham, NG7 2UH, UK. robert.dineen@nhs.net
- Neuroradiology. 2004 Apr 1; 46 (4): 301-5.
AbstractTo date, intracranial aneurysms have been reported in two patients with Noonan syndrome. We report two unrelated patients with Noonan syndrome who presented with sub-arachnoid haemorrhage secondary to intracranial aneurysms. These cases are discussed and other cerebrovascular abnormalities that have been described in association with Noonan syndrome are reviewed. Ultrastructural and genetic factors contributing to these associations are considered.
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