• Maren S Fragala, Dov Shiffman, and Charles E Birse.
• Quest Diagnostics, 500 Plaza Dr, Secaucus, NJ 07094. Email: maren.s.fragala@questdiagnostics.com.
• Am J Manag Care. 2019 Nov 1; 25 (11): 548-553.

ObjectivesEarly detection of disease enables prompt treatment that can prevent disease progression and costly health outcomes. We report incidence of previously unrecognized disease and investigate the expected effect of early detection and care on health outcomes.Study DesignPopulation health study based on laboratory evidence.MethodsLaboratory evidence of prediabetes, diabetes, chronic kidney disease, and colorectal cancer was evaluated in an employee and spouse population (65% women; mean [SD] age = 46 [12] years). Expected disease progression was assessed.ResultsAnnual screening found laboratory evidence for 1185 previously unrecognized cases of prediabetes, 287 cases of diabetes, 73 cases of chronic kidney disease, and 669 positive colorectal screens per 10,000 people.ConclusionsEarly identification and appropriate medical care may delay 34 cases of end-stage kidney disease and prevent diabetes-related complications, 210 cases of diabetes, and 3 cases of late-stage colorectal cancer over 5 years per 1000 cases identified.

26 keywords...

hide…