• Pak J Med Sci · Jan 2019

    Etiology and outcomes of convulsive status epilepticus in children.

    • Muhammad Uzair, Asif Ibrahim, Faisal Zafar, and Tipu Sultan.
    • Dr. Muhammad Uzair MBBS, FCPS (Pediatrics), Fellow Pediatrics Neurology, Department of Pediatric Neurology, Children Hospital Lahore, Pakistan.
    • Pak J Med Sci. 2019 Jan 1; 35 (3): 620-623.

    ObjectiveThe study aimed to ascertain different causes and outcomes of convulsive status epilepticus in children.MethodsFrom January 2018 to June 2018, seventy three patients who presented with status epilepticus were studied. Data were recorded with the help of a pre-formed performa. Etiological factors and outcomes in terms of recovery, morbidity and mortality were studied.ResultsOut of 73 children, forty one (56%) were males and 32(44%) were females with median age of 1.09±0.27 years. Etiologies were acute symptomatic 25(34%), febrile 19(26%), progressive encephalopathy 10(14%), remote symptomatic 10(14%) and idiopathic 7 (9%) with p-value 0.005. Status epilepticus was controlled within one hour in 42(57%), within 1-6 hours in 21(29%) and more than 6 hours in 10(14%) patients with p-value 0.027. During hospitals stay, twenty one (29%) patients recovered completely, seizure recurred in 12(16%), Twelve (16%) became mentally retarded, Twelve (16%) developed mental retardation along with seizures and 16(22%) died. Eight (10.9%) deaths were attributed to acute symptomatic etiology with p-value less than 0.001.ConclusionThis study concluded that acute symptomatic etiology was more common cause of status epilepticus as compared to other etiologies and it is associated with poorer outcomes as compared to other etiologies.

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