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- Zaeem Arif Abbasi, Naila Irum Hadi, Adnan Mustafa Zubairi, and Mervyn Hosein.
- Dr. Zaeem Arif Abbasi, BDS., Ziauddin University, 4/B, Sharah-e-Ghalib, Block 6, Clifton, Karachi, Pakistan.
- Pak J Med Sci. 2019 Jan 1; 35 (3): 674-679.
ObjectivesAim of our study was to assess the expression of salivary Interleukin 1-beta (IL-1β) and clinical periodontal parameters in naswar users and non-users (controls).MethodsEighty four individuals (forty-two naswar users and forty-two controls) were included in the study which was conducted between August 2017 and May 2018. Salivary IL-1β levels, plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL) was assessed in all the participants.ResultsPD of 4mm (p<0.05), PD of 5-6mm (p<0.05), CAL (p<0.001) and levels of salivary IL-1β (p<0.05) were significantly higher among naswar users as compared to controls while PI, BOP and number of missing teeth showed no significant difference among the two groups (p>0.05).ConclusionPeriodontal inflammatory conditions were worse and salivary IL-1β levels were elevated in naswar users as compared to controls.
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