• Am. J. Med. Sci. · Jan 2021

    Review

    Hypertension and Hyperthyroidism: Association and Pathogenesis.

    • Ana M Rivas, Camilo Pena, Jonathan Kopel, Jeff A Dennis, and Kenneth Nugent.
    • Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, U.S.A.. Electronic address: marcella.rivas@ttuhsc.edu.
    • Am. J. Med. Sci. 2021 Jan 1; 361 (1): 3-7.

    AbstractHypertension can cause significant morbidity and reduced life expectancy. Most patients with hypertension have primary hypertension; however, 10 to 15% of patients have secondary hypertension. Endocrine disorders explain approximately 10% of hypertension in all patients, and thyroid disorders account for approximately 1% of cases with hypertension. Hyperthyroidism can cause increased cardiac output, increased systolic blood pressures, and increased levels of renin, angiotensin, and aldosterone. Treatment of hyperthyroidism can cure hypertension in some patients. Consequently, identification of patients with secondary hypertension potentially has important benefits, and understanding secondary hypertension provides a framework for investigating the pathophysiology of hypertension. Clinicians should consider the possibility of hyperthyroidism in patients with hypertension, even in those of more advanced age.Copyright © 2020. Published by Elsevier Inc.

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