• Young Hye Cho, Sang Yeoup Lee, Dong Wook Jeong, Eun Jung Choi, Kyung Jee Nam, Yun Jin Kim, Jeong Gyu Lee, Yu Hyone Yi, Young Jin Tak, Byung Mann Cho, Soo Bong Lee, and Ka Young Lee.
• Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Yangsan, South Korea.
• J Res Med Sci. 2014 Jul 1; 19 (7): 599-604.

BackgroundLow urine pH is related to obesity and insulin resistance, which are components of metabolic syndrome (MS). The aim of this study was to identify the relation between a low urine pH and MS after controlled for other covariates including demographic and lifestyle factors in adult Korean population.Materials And MethodsWe analyzed data from the 2010 Korea National Health and Nutrition Examination Survey, a cross-sectional and nationally representative survey and 1960 men and 2702 women were included in this study. Study subjects were divided into the group with urine pH <5.5 and the group with urine pH ≥5.5 refer to literature. We then evaluated the association between low urine pH and MS.ResultsAfter adjusting for age, sex, smoking status, drinking status, regular exercise, and blood urea nitrogen level, the odds ratio (OR) for the presence of MS in the group with urine pH <5.5 was 1.350 (95% confidence interval [95% CI]: 1.158-1.573) using the American Heart Association/National Heart, Lung, and Blood Institute criteria or 1.304 (95% CI: 1.082-1.572) using the International Diabetes Federation criteria. Among MS components, elevated fasting glucose (OR: 1.231, 95% CI: 1.058-1.433, P = 0.007) and elevated triglyceride (TG) (OR: 1.389, 95% CI: 1.189-1.623, P < 0.001) showed a significantly high OR.ConclusionThe findings confirmed that low urine pH is associated with MS in the Korean population. Among MS components, elevated fasting glucose and elevated TG showed a significantly high OR.

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