• Emerging Infect. Dis. · Nov 2017

    Lineage-Specific Real-Time RT-PCR for Yellow Fever Virus Outbreak Surveillance, Brazil.

    • Carlo Fischer, Maria C Torres, Pranav Patel, Andres Moreira-Soto, Ernest A Gould, Rémi N Charrel, Xavier de Lamballerie, Nogueira Rita Maria Ribeiro RMR, Patricia C Sequeira, Cintia D S Rodrigues, Beate M Kümmerer, Christian Drosten, Olfert Landt, Bispo de Filippis Ana Maria AM, and Jan Felix Drexler.
    • Emerging Infect. Dis. 2017 Nov 1; 23 (11).

    AbstractThe current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.

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