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- Vicente Benavides-Cordoba.
- Universidad del Valle, Facultad de Salud, Escuela de Ciencias Básicas. Cali, Colombia.
- Colomb Medica. 2020 Jun 30; 51 (2): e4279.
AbstractDrug repositioning is a strategy that identifies new uses of approved drugs to treat conditions different from their original purpose. With the advance of COVID-19 and the pandemic declaration; It has become the closest alternative to reduce the advance of the virus. Antimalarial, antiviral drugs, antibiotics, glucocorticoids, monoclonal antibodies, among others, are being studied; their findings, although preliminary, could establish a starting point in the search for a solution. In this review, we present a selection of drugs, of different classes and with potential activity against COVID-19, whose trials are ongoing; and as proofs of concept, double blind, add-on event-driven, would allow proposing research that generates results in less time and preserving quality criteria for drug development and approval by regulatory agencies.Copyright © 2020 Colombia Medica.
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