• María Lucía Pérez Pérez, Ana Gonzaga López, Bárbara Balandín Moreno, Constanza Maximiano Alonso, Diego Palacios Castañeda, José Ferreres Franco, Javier García Sanz, Héctor Villanueva Fernández, Miguel Valdivia de la Fuente, Alfonso Ortega López, Sara Alcántara Carmona, Marina Pérez Redondo, and Ana Royuela Vicente.
• Servicio de Medicina Intensiva, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
• Med Clin (Barc). 2019 Oct 11; 153 (7): 270-275.

Background And ObjectiveTo describe the characteristics and the evolution of patients with solid tumours admitted to the ICU and to identify factors associated with hospital mortality and to evaluate three illness severity scores.Material And MethodsDescriptive study including 132 patients with solid tumour admitted to the ICU (2010-2016). Demographics and cancer-related data, organ failures, life-supporting therapies and severity scores: APACHE II, SOFA and ICU Cancer Mortality Model (ICMM) were collected.ResultsThere were 58 patients admitted for medical reasons and 74 for scheduled surgery. The ICU and hospital mortality rate were 12.9% and 19.7%, respectively. The medical reason for admission, the number of organ failures, and the need of life-supporting therapies were significantly associated with a higher mortality (p<0.05). In the logistic regression analysis, the three severity scores: SOFA (OR 1.18, 95% IC 1.14-1.48), APACHE II (OR 1.11, 95% CI 1.09-1.27), and ICMM (OR 1.03, 95% CI 1.02-1.07) were independently associated with a higher mortality (p<0.05). To evaluate the discrimination, the area under the receiver operating characteristics curves (AUROC) were calculated: APACHE II (0.795, 95% CI 0.69-0.9), SOFA (0.77, 95% CI 0.69-0.864) and ICMM (0.794, 95% CI 0.697-0.891). The comparison of AUC ROC after DeLong's test showed no difference between them.ConclusionHospital mortality was associated with the type and severity of acute illness. The three severity scores were useful to assess outcome and accurate in the discrimination, but we did not find a significant difference between them.Copyright © 2019 Elsevier España, S.L.U. All rights reserved.

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