• Acta paediatrica · Jul 1999

    Case Reports

    Cardiac myxoma in a 6-year-old child--constitutional symptoms mimicking rheumatic disease and the role of interleukin-6.

    • H H Hövels-Gürich, M C Seghaye, B K Amo-Takyi, W Hügel, J Duchateau, and G von Bernuth.
    • Department of Pediatric Cardiology, Aachen University of Technology, Germany.
    • Acta Paediatr. 1999 Jul 1; 88 (7): 786-8.

    AbstractA 6-y-old girl with right atrial myxoma presented with remittent fever attacks, general arthralgia and laboratory investigations mimicking rheumatic or autoimmune disease. Interleukin-6 (IL-6) serum concentration was markedly elevated before and normal after tumour resection, whereas myxoma cells stained negatively for IL-6. IL-6 should be considered a myxoma marker: overproduction by myxoma cells and consecutive systemic passage are assumed to cause immunological features.

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