• Anesteziol Reanimatol · Sep 1998

    Review Comparative Study

    [Analgesic agents: comparative evaluation, mechanisms of action, prospects].

    • V V Churiukanov.
    • Anesteziol Reanimatol. 1998 Sep 1 (5): 4-11.

    AbstractA classification of analgesics based on the localization and mechanisms of their action is proposed. Opioid analgesics are compared: opioid receptor agonists, agonists-antagonists, and partial agonists. Central-action nonopioid analgesics are listed: alpha 2-adrenomimetics, Na- and K-channel blockers, reverse monoamine neuronal capture inhibitors, stimulating amino acid antagonists, etc. Peripheral-action analgesics (cycloxygenase inhibitors) are described.

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