• Chunxue Bai, Sanjay H Chotirmall, Jordi Rello, George A Alba, Leo C Ginns, Jerry A Krishnan, Robert Rogers, Elisabeth Bendstrup, Pierre-Regis Burgel, James D Chalmers, Abigail Chua, Kristina A Crothers, Abhijit Duggal, Yeon Wook Kim, John G Laffey, Carlos M Luna, Michael S Niederman, Ganesh Raghu, Julio A Ramirez, Jordi Riera, Oriol Roca, Maximiliano Tamae-Kakazu, Antoni Torres, Richard R Watkins, Miriam Barrecheguren, Mirko Belliato, Hassan A Chami, Rongchang Chen, Gustavo A Cortes-Puentes, Charles Delacruz, Margaret M Hayes, Heunks Leo M A LMA Dept of Intensive Care, Amsterdam University Medical Center, Amsterdam, The Netherlands., Steven R Holets, Catherine L Hough, Sugeet Jagpal, Kyeongman Jeon, Takeshi Johkoh, May M Lee, Janice Liebler, Gerry N McElvaney, Ari Moskowitz, Richard A Oeckler, Iñigo Ojanguren, Anthony O'Regan, Mathias W Pletz, Chin Kook Rhee, Marcus J Schultz, Enrico Storti, Charlie Strange, Carey C Thomson, Francesca J Torriani, Xun Wang, Wim Wuyts, Tao Xu, Dawei Yang, Ziqiang Zhang, and Kevin C Wilson.
• Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China.
• Eur Respir Rev. 2020 Sep 30; 29 (157).

BackgroundCoronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.MethodsAn International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion.ResultsThe Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder.ConclusionsThe Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.Copyright ©ERS 2020.

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