• Yonsei medical journal · Jul 2013

    Associations of moderate to severe asthma with obstructive sleep apnea.

    • Min Kwang Byun, Seon Cheol Park, Yoon Soo Chang, Young Sam Kim, Se Kyu Kim, Hyung Jung Kim, Joon Chang, Chul Min Ahn, and Moo Suk Park.
    • Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea.
    • Yonsei Med. J. 2013 Jul 1; 54 (4): 942-8.

    PurposeThis study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA).Materials And MethodsOne hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered breathing were evaluated. All subjects were screened with ApneaLink. Thirty-two subjects with a high likelihood of having OSA were assessed with full polysomnography (PSG).ResultsThe mean age was 58.8±12.0 years and 58.7% of subjects were male. The mean ApneaLink apnea-hypopnea index (AHI) was 12.7±13.0/hr. The mean ApneaLink AHI for the 32 selected high risk patients of OSA was 22.3±13.2/hr, which was lower than the sleep laboratory-based PSG AHI of 39.1±20.5/hr. When OSA was defined at an ApneaLink AHI≥5/hr, the positive correlating factors for OSA were age, male gender, and moderate to severe asthma.ConclusionModerate to severe asthma showed strong correlation with OSA when defined at an ApneaLink AHI≥5/hr.

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