• Xuanxuan Chen, Sze Ying Thong, Yong Yeow Chong, and Shin Yi Ng.
• Department of Anaesthesiology, Singapore General Hospital, Singapore.
• Singap Med J. 2016 Mar 1; 57 (3): 126-31.

IntroductionPerioperative anaphylaxis is an anaesthetic emergency, but its incidence is not well described in the local literature. This retrospective study aims to look at a group of patients who had perioperative anaphylaxis in our institution.MethodsWe conducted a retrospective review of electronic databases and clinical case sheets, and identified 34 patients who had possible perioperative anaphylaxis during anaesthesia in our institution between 1 January 2007 and 30 April 2012.ResultsAfter reviewing clinical and biochemical data, we found that 16 out of 151,876 patients who underwent surgery had confirmed perioperative anaphylaxis, an incidence of 1:10,000. Neuromuscular blockers were identified as the most common causative agent for perioperative anaphylaxis. The offending agent could not be identified in seven patients.ConclusionTo the best of our knowledge, this is the first study in Southeast Asia on the incidence of perioperative anaphylaxis. Having a preoperative history of allergy did not seem to predispose patients to the subsequent development of perioperative anaphylaxis.Copyright: © Singapore Medical Association.

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