• The Medico-legal journal · Jul 2020

    Thromboinflammatory response in SARS-CoV-2 sepsis.

    • Aniello Maiese, Giovanna Passaro, Alessandra DE Matteis, Valentina Fazio, La Russa Raffaele, and Paolo Marco Di MD Department of Surgical Pathology, Medical, Molecular and Critical Area, Institute of Legal Medicine, University of Pisa, Pisa, Italy..
    • Department of Surgical Pathology, Medical, Molecular and Critical Area, Institute of Legal Medicine, University of Pisa, Pisa, Italy.
    • Med Leg J. 2020 Jul 1; 88 (2): 78-80.

    AbstractViral sepsis is rare, and its real incidence is not known. SARS-CoV-2 infection causes the release of a significant amount of pro-inflammatory cytokines that aggravates interstitial pneumonia and evolves in viral sepsis with prominent hypercoagulability. We believe it is useful and advisable to establish early immunomodulator therapy and the prophylaxis anticoagulant therapy should be rethought.

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