• Am. J. Obstet. Gynecol. · May 2003

    Randomized Controlled Trial Clinical Trial

    Local anesthetic reduces the pain of colposcopic biopsies: a randomized trial.

    • Ian A Oyama, Mark T Wakabayashi, LeighAnn C Frattarelli, and Bruce Kessel.
    • Department of Obstetrics and Gynecology and Women's Health, John A. Burns School of Medicine, University of Hawaii, HI, USA.
    • Am. J. Obstet. Gynecol. 2003 May 1; 188 (5): 1164-5.

    ObjectiveThis study was undertaken to determine whether administration of local anesthetic reduces pain associated with colposcopically directed cervical biopsies.Study DesignFifty-six patients undergoing colposcopically directed cervical biopsies were randomly selected prospectively to receive a 1% lidocaine injection or no injection before the biopsy procedure. Pain was assessed by using a 10-cm visual analog scale at various points during the procedure. Data were analyzed with the Student t test.ResultsInjection of lidocaine resulted in a reduction in pain scores for cervical biopsies (4.004 to 1.166, P: <.001), endocervical curettage (5.757 to 3.900, P =.0018), and overall procedure scores (4.911 to 3.145, P =.0013).ConclusionThis pilot study demonstrates that injection of local anesthetic at the site of colposcopically direct cervical biopsies decreases the pain perceived by patients.

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