• Am J Manag Care · Apr 2011

    Randomized Controlled Trial

    A multimodal blood pressure control intervention in 3 healthcare systems.

    • David J Magid, P Michael Ho, Kari L Olson, David W Brand, Lesley K Welch, Karen E Snow, Anne C Lambert-Kerzner, Mary E Plomondon, and Edward P Havranek.
    • Institute for Health Research, Kaiser Permanente Colorado, Denver, USA. david.j.magid@kp.org
    • Am J Manag Care. 2011 Apr 1; 17 (4): e96-103.

    ObjectiveTo determine if a multimodal intervention composed of patient education, home blood pressure (BP) monitoring, BP measurement reporting to an interactive voice response (IVR) phone system, and clinical pharmacist follow-up improves BP control compared with usual care.Study DesignProspective study with patient enrollment, medication consultation and adjustment, remote BP monitoring, and follow-up at 6 months.MethodsThis randomized controlled trial was conducted at 3 healthcare systems in Denver, Colorado, including a large health maintenance organization, a Veterans Affairs medical center, and a county hospital. At each site, patients with uncontrolled BP were randomized to the multimodal intervention vs usual care for 6 months, with the primary end point of BP reduction.ResultsOf 338 patients randomized, 283 (84%) completed the study, including 138 intervention patients and 145 usual care patients. Baseline BP was higher in the intervention group vs the usual care group (150.5/89.4 vs 143.8/85.3 mm Hg). At 6 months, BPs were similar in the intervention group vs the usual care group (137.4 vs 136.7 mm Hg, P = .85 for systolic; 82.9 vs 81.1 mm Hg, P = .14 for diastolic). However, BP reductions were greater in the intervention group vs the usual care group (−13.1 vs −7.1 mm Hg, P = .006 for systolic; −6.5 vs −4.2 mm Hg, P = .07 for diastolic). Adherence to medications was similar between the 2 groups, but intervention patients had a greater increase in medication regimen intensity.ConclusionsA multimodal intervention of patient education, home BP monitoring, BP measurement reporting to an IVR system, and clinical pharmacist follow-up achieved greater reductions in BP compared with usual care.

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