• Hyung Seok Lee, Hye Sun Lee, Hyo Eun Lee, Mi Kyung Bae, Kyung Young Chung, Ha Young Shin, Young-Chul Choi, and Seung Min Kim.
• Department of Neurology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
• Muscle Nerve. 2015 Aug 1; 52 (2): 216-20.

IntroductionPredictive factors for myasthenic crisis after transsternal thymectomy have been reported, but little is known about myasthenic crisis after videoscopic thymectomy (MCAVT).MethodsWe investigated 146 myasthenia gravis patients who underwent videoscopic thymectomy.ResultsPatients with MCAVT had a lower forced vital capacity (FVC) (2.1 vs. 3.0 L, P < 0.001) than those without. Low-frequency repetitive nerve stimulation showed decremental responses of the orbicularis oculi (47.1% vs. 18.1%, P = 0.001) and nasalis muscles (54.1% vs. 21.4%, P < 0.001), which were more pronounced in patients with MCAVT than those without. According to multivariate analysis, FVC (OR 0.144, 95% confidence interval [CI], 0.044-0.479, P = 0.002) and decremental response of orbicularis oculi (odds ratio, 1.029; 95% CI, 1.001-1.058, P = 0.044) were independently associated with MCAVT.ConclusionsFVC and decremental response of orbicularis oculi were associated with MCAVT.© 2014 Wiley Periodicals, Inc.

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