• Jose María Lloreda-Garcia, Ana Lorente-Nicolás, Francisca Bermejo-Costa, Juan Martínez-Uriarte, and Rocío López-Pérez.
• Unidad de Cuidados Intensivos Neonatales, Servicio de Pediatría, Hospital General Universitario Santa Lucía, Cartagena, Murcia, España. Electronic address: jmlloreda@gmail.com.
• Rev Chil Pediatr. 2016 Jul 1; 87 (4): 261-7.

IntroductionMagnesium sulphate administration is recommended for foetal neuroprotection in pregnant women at imminent risk of early preterm birth.ObjectiveTo evaluate the relationship between intrapartum magnesium sulphate for foetal neuroprotection and delivery room resuscitation of preterm infants less 32 weeks.Patients And MethodA prospective observational study was conducted on preterm infants less 32 weeks exposed to magnesium sulphate for neuroprotection, and a comparison made with another historic group immediately before starting this treatment. Cases in both groups that had not reached lung maturity with corticosteroids were rejected. The rates of resuscitation, morbidity and mortality for each of the groups were analysed and compared.ResultsThere was a total of 107 preterm, with 56 exposed to magnesium sulphate. Rate of advanced resuscitation were similar between the two groups. There were no other differences in mortality, invasive mechanical ventilation, time to first stool, and other comorbidities.ConclusionsIntrapartum magnesium sulphate for foetal neuroprotection was not associated with an increased need for intensive delivery room resuscitation and other morbidities in these cohorts of less than 32 weeks preterm infants.Copyright © 2015 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

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