• Drug Discov Ther · Jan 2020

    Review

    Rapid review for the anti-coronavirus effect of remdesivir.

    • Ziyi Li, Xiaojie Wang, Donglin Cao, Ruilin Sun, Cheng Li, and Guowei Li.
    • Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
    • Drug Discov Ther. 2020 Jan 1; 14 (2): 73-76.

    AbstractThe outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification.

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