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- L Nikolajsen and M Lindvig.
- Arhus Universitetshospital, Arhus Kommunehospital, Dansk Smerteforskningscenter. nikolajsen@dadlnet.dk
- Ugeskr. Laeg. 2001 Jun 11; 163 (24): 3338-41.
AbstractPhantom pain is experienced by about 70% of patients following limb amputation. In most patients, both the frequency and the intensity of pain attacks diminish with time, but severe pain persists in about 5-10%. The mechanisms underlying pain in amputees are not fully understood, but factors in both the peripheral and central nervous system play a role. Pain before the amputation seems to increase the risk of phantom pain, but the relation is not simple. Treatment of phantom pain is not successful; a recent study on prevention of the pain with a preoperative epidural blockade showed negative results. The future may reveal new specific drugs for treatment.
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