• Clin. Infect. Dis. · Jun 2009

    Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center.

    • Joshua D Hartzell, Robert Neff, Julie Ake, Robin Howard, Stephen Olson, Kristopher Paolino, Mark Vishnepolsky, Amy Weintrob, and Glenn Wortmann.
    • US Army, Infectious Diseases Service, Walter Reed Army Medical Center, Bldg. 2, Ward 63, 6900 Georgia Ave. NW, Washington, DC 20307, USA. joshua.hartzell@amedd.army.mil
    • Clin. Infect. Dis. 2009 Jun 15; 48 (12): 1724-8.

    AbstractThe incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.

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