• Thrombosis research · Oct 2017

    Multicenter Study

    Evaluation of dabigatran, rivaroxaban and apixaban target-specific assays in a multicenter French study.

    • Isabelle Gouin-Thibault, Geneviève Freyburger, Emmanuel de Maistre, Sophie Susen, Xavier Delavenne, Jean-Louis Golmard, Yves Gruel, Pierre Sié, and GFHT study group on DOAC.
    • INSERM UMR_S1140, Faculté de Pharmacie, Paris, France; Laboratoire d'Hématologie, Centre Hospitalier Universitaire, Rennes, France. Electronic address: isabelle.gouin@chu-rennes.fr.
    • Thromb. Res. 2017 Oct 1; 158: 126-133.

    AbstractDabigatran etexilate, rivaroxaban and apixaban (DOACs) are widely used and measurement of their concentration is desirable in certain clinical situations. Target-specific assays are available but limited information exists on their performance especially in their ability to accurately measure low and high concentrations.Copyright © 2017 Elsevier Ltd. All rights reserved.

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