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J. Thromb. Haemost. · Nov 2016
Multicenter Study Comparative Study Observational StudyPoor comparability of coagulation screening test with specific measurement in patients receiving direct oral anticoagulants: results from a multicenter/multiplatform study.
- S Testa, C Legnani, A Tripodi, O Paoletti, V Pengo, R Abbate, L Bassi, P Carraro, M Cini, R Paniccia, D Poli, and G Palareti.
- Department of Laboratory Medicine, Hemostasis and Thrombosis Center, AO Istituti Ospitalieri, Cremona, Italy.
- J. Thromb. Haemost. 2016 Nov 1; 14 (11): 2194-2201.
AbstractEssentials Prothrombin and partial thromboplastin time (PT/PTT) measure direct oral anticoagulants (DOACs). PT, PTT and specific tests for DOACs were performed on patients treated for atrial fibrillation. Normal PT/PTT don't exclude DOAC activity and their prolongation doesn't confirm DOAC action. The use of PT or PTT to evaluate DOAC activity could cause dangerous misinterpretations.© 2016 International Society on Thrombosis and Haemostasis.
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