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- Gaurav Aggarwal, Giuseppe Lippi, and Michael Henry Brandon B Cardiac Intensive Care Unit, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, USA..
- Department of Medicine, Jersey City Medical Center, Jersey City, USA.
- Int J Stroke. 2020 Jun 1; 15 (4): 385-389.
IntroductionThere is an urgent need to identify patients at high risk during the ongoing coronavirus disease (COVID-19) pandemic. Whether a history of stroke is associated with increased severity of disease or mortality is unknown.MethodWe pooled studies from published literature to assess the association of a history of stroke with outcomes in patients with COVID-19.ResultsA pooled analysis of 4 studies showed a ∼2.5-fold increase in odds of severe COVID-19. While a trend was observed, there was no statistically significant association of stroke with mortality in patients with COVID-19 infection.DiscussionOur findings are limited by a small number of studies and sample size.ConclusionThere is a ∼2.5-fold increase in odds of severe COVID-19 illness with a history of cerebrovascular disease.
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