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Acta Otorrinolaringol Esp · Mar 2017
Hypoparathyroidism following thyroidectomy: Predictive factors.
- Cristiana Coimbra, Francisco Monteiro, Pedro Oliveira, Leandro Ribeiro, Mário Giesteira de Almeida, and Artur Condé.
- Centro Hospitalar Vila Nova de Gaia Espinho (CHVNGE), ENT Department, Gaia, Portugal. Electronic address: cfilipa.coimbra@gmail.com.
- Acta Otorrinolaringol Esp. 2017 Mar 1; 68 (2): 106-111.
ObjectiveTo evaluate the incidence and predictive factors for transient and permanent hypocalcemia and hypoparathyroidism following thyroidectomy.MethodWe studied all the 162 patients that underwent thyroid surgery in the ENT department of the Centro Hospitalar Vila Nova Gaia/Espinho from January 2005 to December 2014. We reviewed pre-operative, 6h and 12h after surgery ionized calcium and PTH levels. All patients were reviewed and evaluated according to the following criteria: gender, age, thyroid function, histologic diagnosis of the specimen, surgery extension and presence or absence of hypoparathyroidism.ResultsThere were 31 (19.1%) cases of transient hypoparathyroidism and 8 (5%) of permanent hypoparathyroidism. No significant difference was found for transient hypoparathyroidism when patients were analyzed by gender. However, all cases of permanent hypoparathyroidism were observed in female individuals. Comparing hemithyroidectomy with all other surgical procedures, we found that extension of surgery was a great predictor of transient (p=0.0001) and permanent (p=0.001) hypoparathyroidism. Diagnosis of malignancy was a strong predictor of transient hypoparathyroidism (p=0.002). It was also associated with permanent hypoparathyroidism, although differences did not reach statistical significance (p=0.096).ConclusionExtension of surgery (total thyroidectomy) and diagnosis of malignancy are predictors of transient and permanent hypoparathyroidism.Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.
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