• Ji Yeon Lee, Hong Seung Wan SW Department of Family Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea., Miri Hyun, Jae Seok Park, Jae Hyuck Lee, Young Sung Suh, Dae Hyun Kim, Seong-Wook Han, Chi-Heum Cho, and Hyun Ah Kim.
• Department of Infectious Disease, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
• Int. J. Infect. Dis. 2020 Sep 1; 98: 462-466.

ObjectivesTwo Coronavirus Disease 2019 (COVID-19) outbreaks simultaneously occurred at a church and a long-term care facility in Daegu, South Korea. This study aimed to investigate the epidemiological characteristics of COVID-19 and factors related to severe outcomes.MethodsWe enrolled all inpatients diagnosed with COVID-19 between February 21 and April 2, 2020, in Daegu Dongsan Hospital. We analyzed their clinical and demographic data, laboratory parameters, radiological findings, symptoms, and treatment outcomes.ResultsOf 694 patients, severe cases accounted for 19.7% (137 patients). No severe case was observed among patients aged ≤19 years. Hypertension was the most common comorbidity (27%), and cough was the most common symptom (59%). Asymptomatic patients accounted for 14.4% of cases. Lymphopenia, lactate dehydrogenase, C-reactive protein, and albumin were associated with severe outcomes. The first outbreak was mostly associated with younger age groups, and asymptomatic patients mostly showed mild progression. In the second outbreak involving a long-term care facility, both the number of severe patients and the mortality rate were higher.ConclusionsThe overall mortality in Daegu was low, which might have resulted from large scale mass screening to detect patients and starting appropriate treatment, including hospitalization for severe cases, and quarantine for asymptomatic patients.Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

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