• Beat Roth, Frédéric D Birkhäuser, Pascal Zehnder, Fiona C Burkhard, George N Thalmann, and Urs E Studer.
• Department of Urology, University of Bern, Bern, Switzerland.
• Eur. Urol. 2011 Feb 1; 59 (2): 204-10.

BackgroundProlonged postoperative pain and delayed intestinal transit are frequent problems following extended pelvic lymph-node dissection (PLND) and cystectomy.ObjectiveTo evaluate the impact of bilateral readaptation of the dorsolateral peritoneal layer on postoperative pain, gastrointestinal recovery, and complications following extended PLND and cystectomy.Design, Setting, And ParticipantsRandomized, single-blinded, single-center study of 200 consecutive cystectomy patients.InterventionIn group A (n=100), lateral peritoneal flaps ventral to the external iliac vessels were bilaterally rotated over the iliac vessels down to the distal obturator fossa and medially fixed to the pararectal peritoneal layer following extended PLND and cystectomy. In group B (n=100), the peritoneal layer was not readapted.MeasurementsPain according to the visual analog scale (VAS), amount of peridural anesthetics needed, and gastrointestinal activity were assessed on postoperative days 1, 3, and 7. Complications occurring within 30 d following surgery were documented.Results And LimitationsReadaptation of the dorsolateral peritoneal layer resulted in a significant decrease in pain (p<0.01) with concurrent significantly reduced need for peridural anesthetics (p<0.01). Flatulence and first passage of stool as signs of intestinal transit were noted earlier in group A than in group B. Gastrostomy tube and peridural catheter could be removed 1 d earlier in group A than in group B (postoperative days 7 vs 8 and 6 vs 7, respectively). Group A (30%) had fewer complications than group B (56%; p<0.001).ConclusionsReadaptation of the dorsolateral peritoneal layer after extended PLND and cystectomy resulted in significantly less postoperative pain, earlier recovery of bowel function, and fewer complications in the early postoperative period.Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.

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