• Zhoujie Peng, Jianhui Wang, Yunbo Mo, Wei Duan, Guangjun Xiang, Ming Yi, Lei Bao, and Yuan Shi.
• Department of Neonatology, Chongqing University Three Gorges Hospital, Department of Neonatology, Chongqing Three Gorges Central Hospital, 165 Xin Cheng Road, Wanzhou District, Chongqing 404000, China.
• J Infect Public Health. 2020 May 1; 13 (5): 818-820.

AbstractAs the 2019 novel coronavirus disease (COVID-19) rapidly spread across China and to more than 70 countries, an increasing number of pregnant women were affected. The vertical transmission potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of great concern to the obstetrics, neonatologists, and public health agencies. Though some studies indicated the risk of vertical transmission is low, few cases have been reported with comprehensive serial tests from multiple specimens. In this case, a female preterm infant was born to a mother with confirmed COVID-19. She presented with mild respiratory distress and received general management and a short period of nasal continuous positive airway pressure support. During her stay at the hospital, a series of SARS-CoV-2 nucleic test from her throat and anal swab, serum, bronchoalveolar lavage fluid, and urine were negative. The nucleic acid test from the mother's amniotic fluid, vaginal secretions, cord blood, placenta, serum, anal swab, and breast milk were also negative. The most comprehensively tested case reported to date confirmed that the vertical transmission of COVID is unlikely, but still, more evidence is needed.Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

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