• Tido von Schoen-Angerer, René Madeleyn, Gunver Kienle, Helmut Kiene, and Jan Vagedes.
• ARCIM Institute, Filderklinik, Filderstadt, Germany Department of Pediatrics, Fribourg Hospital HFR, Fribourg, Switzerland tido.von.schoenangerer@gmail.com.
• J. Child Neurol. 2015 Jul 1; 30 (8): 1048-52.

AbstractViscum album (European mistletoe) extracts have known immunomodulatory effects but little data exist on anticonvulsant activity despite its usefulness having been reported for centuries. A 4½-year-old girl with childhood absence epilepsy and global developmental delay was treated with different antiepileptic drugs and ketogenic diet but failed to become seizure free over a 2-year period. She also received different herbal remedies as part of an integrative medicine approach. Initial improvement occurred on valproate-ethosuximide, a further improvement was seen after adding clobazam to valproate. Final cessation of absence activity occurred after a dose increase of V album. She was still seizure free at the 12-month follow-up. V album appears to have been a necessary adjunct treatment for this child to become seizure free. We call on physicians to report their experiences of V album in epilepsy and suggest further study. © The Author(s) 2014.

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