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Randomized Controlled Trial Clinical Trial
Itching Caused by TRPV3 (Transient Receptor Potential Vanilloid-3) Activator Application to Skin of Burn Patients.
- Hye One Kim, Kim Jin Cheol, Kong Yu Gyeong, and Kwak In Suk.
- Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul 07441, Korea.
- Medicina (Kaunas). 2020 Oct 25; 56 (11).
AbstractBackground and objectives: Postburn pruritus is a common complication of scars in burn patients. In our previous study, we discovered increased expression of TRPV3, TRPV4, and TRPA1. Among them, TRPV3, in particular, is predominantly expressed in the epidermis of the tissue of pruritic burn scars. We sought to evaluate the correlation between the expression of TRPV3 activators and itching after application of TRPV3 activator carvacrol over burn scars. Materials and Methods: Design: This was a double-blind clinical trial with non-randomized distribution.
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