• BMJ case reports · Sep 2015

    Case Reports

    Delayed full-thickness macular hole closure without vitreomacular traction release following ocriplasmin injection.

    • Sleiman Abou Ltaif and Luke Herbert.
    • Eye Unit, East Surrey Hospital, Redhill, Surrey, UK.
    • BMJ Case Rep. 2015 Sep 10; 2015.

    AbstractWe report a case of a 77-year-old Caucasian woman, treated with ocriplasmin injection for vitreomacular traction (VMT) and full-thickness macular hole (FTMH), who had a persistence outer retinal defect on her 28-day review, without VMT resolution, then presented 3 months later with complete macular hole closure, with persistence of vitreomacular adhesion. This case raises the question on the validity of the 28-day fixed date to assess final outcome of ocriplasmin injection for FTMH associated with VMT, and sheds new lights on the behaviour of the posterior hyaloid in cases of vitreolysis by a chemical agent such as ocriplasmin. 2015 BMJ Publishing Group Ltd.

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