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- H Brenner.
- Div. of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany. H.Brenner@dkfz.de
- Z Gastroenterol. 2008 Apr 1; 46 Suppl 1: S20-2.
AbstractEpidemiological evidence suggests that incidence of colorectal cancer can be reduced by 60-90% among participants of preventive colonoscopy with removal of precancerous lesions. Even with sigmoidoscopy, the majority of cancers can be prevented. Cost-effectiveness analyses suggest screening schemes based on colonoscopy every 10 years or on sigmoidoscopy every 5 years to be highly cost effective compared to other preventive measures. Even higher cost-effectiveness is to be expected if screening intervals can be extended to 20 or more years, as suggested by recent epidemiological evidence.
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