• Christine A Blauvelt, Catherine Chiu, Anne L Donovan, Mary Prahl, Thomas K Shimotake, Ronald B George, Brian S Schwartz, Naghma A Farooqi, Syed S Ali, Arianna Cassidy, Juan M Gonzalez, and Stephanie L Gaw.
• Department of Obstetrics, Gynecology, & Reproductive Sciences, the Divisions of Critical Care Medicine and Obstetric Anesthesia, Department of Anesthesia and Perioperative Care, the Divisions of Pediatric Infectious Diseases and Neonatology, Department of Pediatrics, the Division of Infectious Diseases, Department of Medicine, and the Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, San Francisco, California.
• Obstet Gynecol. 2020 Jul 1; 136 (1): 46-51.

BackgroundData suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being.CaseWe report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative.ConclusionWe describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.

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