• Clin Plast Surg · Oct 2015

    Review

    Coming of Age: Breast Implant-Associated Anaplastic Large Cell Lymphoma After 18 Years of Investigation.

    • Mark W Clemens and Roberto N Miranda.
    • Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1488, Houston, TX 77030, USA. Electronic address: mwclemens@mdanderson.org.
    • Clin Plast Surg. 2015 Oct 1; 42 (4): 605-13.

    AbstractBreast implant associated anaplastic large cell lymphoma (BIALCL) is a distinct clinical entity that can present in patients receiving either reconstructive or cosmetic breast implants. Presenting symptoms include onset of a delayed (>1 year after implantation) fluid collection, mass of the capsule, or lymphadenopathy. Treatment has progressed in recent years and most commonly includes implant removal and total resection of the tumor, including capsule, mass, and involved lymph nodes. Further research is warranted to determine potential malignant drivers, disease progression, and optimal treatment strategies in advanced disease. Copyright © 2015 Elsevier Inc. All rights reserved.

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