• Eur. J. Immunol. · Jul 2020

    COVID-19 vaccines: Knowing the unknown.

    • Huibin Lv, Nicholas C Wu, and Mok Chris K P CKP 0000-0002-0525-6772 HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong.
    • HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
    • Eur. J. Immunol. 2020 Jul 1; 50 (7): 939-943.

    AbstractVaccine development against SARS-CoV-2 has drawn attention around the globe due to the exploding pandemic. Although COVID-19 is caused by a new coronavirus, SARS-CoV-2, previous research on other coronavirus vaccines, such as FIPV, SARS, and MERS, has provided valuable information for the rapid development of COVID-19 vaccine. However, important knowledge gaps remain - some are specific to SARS-CoV-2, others are fundamental to immunology and vaccinology. Here, we discuss areas that need to be addressed for COVID-19 vaccine development, and what can be learned from examples of vaccine development in the past. Since the beginning of the outbreak, the research progress on COVID-19 has been remarkable. We are therefore optimistic about the rapid development of COVID-19 vaccine.© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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