• Cardiology clinics · May 2015

    Review

    Statins and cognitive side effects: what cardiologists need to know.

    • Carlos Rojas-Fernandez, Zain Hudani, and Vera Bittner.
    • Schlegel-UW Research Institute for Ageing & School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada; School of Public Health and Health Systems, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario, Canada; Michael G. DeGroote School of Medicine, Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address: carlos.rojas-fernandez@uwaterloo.ca.
    • Cardiol Clin. 2015 May 1; 33 (2): 245-56.

    AbstractStatins are widely used in secondary and primary prevention of atherosclerotic cardiovascular disease. They reduce cardiovascular events and mortality, and have an excellent safety record. Recent case reports suggest a possible association between statins and adverse effects on cognition. This article reviews recent literature related to statins and cognition and provides recommendations to clinicians. Cognitive considerations should not play a role in decision making for most patients for whom statins are indicated. Future trials of statin, or any novel antilipemic agent should include systematic assessment of cognition.Copyright © 2015 Elsevier Inc. All rights reserved.

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